12 days in Lesbos Itinerary

12 days in Lesbos Itinerary

Created using Inspirock Lesbos tour itinerary maker

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Make it your trip
Fly
1
Mytilene
— 5 nights
Drive
2
Molyvos
— 6 nights
Drive to Mytilene International Airport, Fly to Amsterdam

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Mytilene

— 5 nights
Founded in the 11th century BCE, Mytilene is the capital of the island of Lesbos.
Mytilene Castle and The Yeni Tzami (Mosque) will appeal to history buffs. Get out of town with these interesting Mytilene side-trips: Panagia Agia Sion (in Agiasos) and Plomari (Ouzo Museum "The World of Ouzo" by Ouzo Plomari Isidoros Arvanitis Distillery & Barbayannis Ouzo Museum). And it doesn't end there: don't miss a visit to Moni Agios Taxiarchis, indulge in some personalized pampering at Therma Spa Mytilene, explore the world behind art at Theriade Library and Museum of Modern Art, and explore the ancient world of The Roman Aqueduct.

Ask Inspirock to suggest an itinerary and make planning a trip to Mytilene fast, fun, and easy.

Amsterdam, The Netherlands to Mytilene is an approximately 7-hour flight. The time zone changes from Central European Standard Time to Eastern European Standard Time, which is usually a 1 hour difference. Traveling from Amsterdam in November, things will get somewhat warmer in Mytilene: highs are around 21°C and lows about 13°C. Wrap up your sightseeing on the 5th (Sun) early enough to drive to Molyvos.

Things to do in Mytilene

Museums · Historic Sites · Spas · Baths

Side Trips

Find places to stay Nov 30 — Dec 5:

Molyvos

— 6 nights
Mithymna is a town and former municipality on the island of Lesbos, North Aegean, Greece. Get some historical perspective at Panagia Glykofilousa and Ypsilou Μonastery. You'll find plenty of places to visit near Molyvos: Moni Agios Taxiarchis (in Parakila), Natural History Museum of the Lesvos Petrified Forest (in Sigri) and Moni Limonos (in Kalloni). The adventure continues: test the waters at Healing Springs of Lesvos: Eftalou, stop by Elleni's Workshop, explore by horseback at Michaelis' Donkey Farm, and explore the ancient world of Temple of Aphrodite.

For ratings, photos, where to stay, and other tourist information, read our Molyvos trip planning tool.

You can drive from Mytilene to Molyvos in 1.5 hours. In December, daytime highs in Molyvos are 15°C, while nighttime lows are 8°C. Wrap up your sightseeing on the 11th (Sat) to allow time to travel back home.

Things to do in Molyvos

Historic Sites · Parks · Trails · Outdoors

Side Trips

Find places to stay Dec 5 — 11:

Lesbos travel guide

3.8
Castles · Beaches · Landmarks
Emerald Isle
Still largely unaffected by commercial tourism, Lesbos maintains its leisurely pace of life and offers visitors a tranquil landscape of lush olive groves and age-old fishing settlements. The Ottomans called this island the "Garden of the Empire," valuing its pristine natural scenery and rich cultural heritage. Lesbos once drew philosophers like Aristotle and Epicurus, who ran a renowned philosophical academy on the island. Today Lesbos' coastline attracts hikers, cyclists, and beachgoers, while its unspoiled forested areas draw ardent birdwatchers. Begin your island adventure at Mytilene, a lively port town packed with museums, churches, and traditional taverns.